| Date | Location | Result | |
| 3/12/06 | Richmond, Va. (Arthur Ashe Center) | Georgia College & State 77, Presbyterian College 58 | Box score |
| 3/11/06 | Richmond, VA (Arthur Ashe Center) | Presbyterian College 73, Armstrong Atlantic 67 | Box score |
| 03/05/06 | Hickory, N.C. (CVCC Arena) | Wingate University 61, Presbyterian College 50 | Box score |
| 03/04/06 | Hickory, N.C. (Catawba Valley CC) | Presbyterian College 67, Tusculum College 62 | Box score |
| 03/01/06 | Clinton, SC (Ross E. Templeton Center) | Presbyterian College 67, Carson-Newman College 64 | Box score |
| 02/25/06 | Salisbury,NC (Goodman Gym) | Catawba Indians 65, Presbyterian Blue Hose 59 | Box score |
| 02/22/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 56, Tusculum College 53 | Box score |
| 02/20/06 | Jefferson City, Tenn./Holt Fieldhouse | Presbyterian 55, Carson-Newman 49 | Box score |
| 02/18/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 80, Lenoir-Rhyne College 62 | Box score |
| 02/15/06 | Newberry, S.C. (Eleazer Arena) | Newberry College 82, Presbyterian College 67 | Box score |
| 02/08/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 80, Wingate University 73 | Box score |
| 02/06/06 | Central, S.C. (J.W. Tysinger Gymnasium) | Presbyterian College 72, Southern Wesleyan University 65 | Box score |
| 02/04/06 | Mars Hill, NC (Stanford Arena) | Presbyterian College 74, Mars Hill College 69 | Box score |
| 01/31/06 | Columbia, S.C. (John Hurst Gymnasium) | Presbyterian College 91, Allen University 48 | Box score |
| 01/28/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 75, Catawba College 69 | Box score |
| 01/25/06 | Greeneville, Tenn. (Pioneer Arena) | Presbyterian 65, Tusculum 50 | Box score |
| 01/21/06 | Hickory, N.C. (Shuford Gymnasium) | Lenoir-Rhyne 69, Presbyterian 55 | Box score |
| 01/18/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 76, Newberry College 72 | Box score |
| 01/14/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 69, Carson-Newman College 67 | Box score |
| 01/11/06 | Wingate, N.C. (Cuddy Arena) | Wingate University 73, Presbyterian 64 | Box score |
| 01/07/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 96, Mars Hill College 74 | Box score |
| 12/30/05 | Clinton, SC (Ross E. Templeton Center) | Georgia College & St. Univ. 79, Presbyterian College 67 | Box score |
| 12/17/05 | Savannah, Ga. (Alumni Arena) | Armstrong Atlantic 65, Presbyterian 56 | Box score |
| 12/16/05 | Savannah, Ga. (Alumni Arena) | #1 University of Montevallo 59, Presbyterian 52 | Box score |
| 12/14/05 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 74, #21 USC Upstate 63 | Box score |
| 12/03/05 | Tigerville, S.C. (Hayes Gymnasium) | Presbyterian College 74, North Greenville University 65 | Box score |
| 11/30/05 | Due West, S.C. (Belk Arena) | Presbyterian College 67, Erskine College 55 | Box score |
| 11/28/05 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 62, Southern Wesleyan University 55 | Box score |
| 11/26/05 | Aiken, S.C. (The Courthouse) | Presbyterian 76, USC Aiken 58 | Box score |
| 11/25/05 | Aiken, S.C. (The Courthouse) | Presbyterian College 77, Lander University 61 | Box score |
| 11/22/05 | Milledgeville, Ga. (Centennial Center) | Presbyterian College 64, Georgia College & State Univ. 61 | Box score |
| 11/16/05 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 83, Allen University 66 | Box score |
| 11/13/05 | Orlando, Fla. (Disney W.W. of Sports) | Presbyterian College 84, Philadelphia University 78 | Box score |
| 11/12/05 | Orlando, Fla. (Disney W.W. of Sports) | Presbyterian College 72, Caldwell College 51 | Box score |
| 11/11/05 | Orlando, Fla. (Disney W.W. of Sports) | #13 Univ. of Nebraska-Omaha 89, Presbyterian College 75 | Box score |